Related article: of "dissolution" of the nervous system, and it "is the merit of Hughlings Jackson in England, and of Charcot and his followers in Cleocin 100 Mg France, to have studied them with preeminent clearness of insight. The point for our notice is that, under the conditions indicated, the multiform nerve functions which, under the normal regime, were kept within their proper channels of usefulness, now, deprived of leadership and control, run riot like a horse that has lost his rider, though it may be, as Dr. Jackson has pointed out, that they act in a real though misguided attempt to meet the exigencies of the movement. It is for this reason, and because even in disease the likeness to normal action is preserved, that the term quasi- physiological is justified. Does all the vast array of symptoms of this mysterious Graves's disease form a Cleocin T Pads confused and accidental jumble, or can we find the bond which unites them? I have already indicated that such a bond has been sought in the anatomical relationship of the nerve centres related to these various symptoms. It has been sought also in the action of some supposed poison generated in consequence of disease of the thyroid gland. Either or both of these hypotheses may be Cleocin Oral true, but behind, and independent of them, there is, I believe, a physiological or quasi-physio- logical bond which unites the symptoms of Graves's disease, and this is of a double nature. 1. They are united by their Order Cleocin Online close relationship to the TREATMENT OF EXOPHTHALMIC GOITRE. Cleocin Antibiotic 625 manifestation of emotion. The trembling hand, the star- ing eyes, the rapidly beating heart, the sweating skin, the husky voice, the relaxed bowels, belong to the picture of painful expectancy and fear. The likeness, though but a caricature, is too Cleocin Topical Gel striking to be mistaken, and has attracted the attention of a number of observers, among whom I will Buy Cleocin T mention McKenzie in England, and Peter and Raymond and Serieux in France, and Buschan in Germany. It is an important advance in conception and definition, rather than a discovery, of Cleocin Suspension modern psychology, to Cleocin Suppositories recog- nize that outward expression not only illustrates but forms an integral part of the mental state with which it occurs. This is eminently true of the emotions, as James, Lange and Fere have clearly shown. An emotion is an intellect- ual cognition plus a host of bodily states which we can only imperfectly analyze and separate. In Graves's disease the first impulse to the outbreak is often, if not usually, an emotional cause. In a case of my own, a woman went down a dark stairway, and at the bot- tom was suddenly seized and roughly handled by a man, and then and there her disease began. Many such cases are on record (see Brain, 1894, p. 221, and Buschan). But, it will be urged, many cases of Graves's disease begin Cleocin 600 Mg insidiously without emotional antecedents, and some- times in such a manner as to make it more than probable that a disease of the thyroid gland, or it may Cleocin Tablets be even an irritation starting in the nasal cavity or elsewhere, set the match to the train. I have observed myself an interesting case where prolonged vomiting gave the first impulse. It is also true that the disease may run its course without being Cleocin Cost associated with any high degree of emotional display. The explanation for this I have already tried to suggest. We cannot tell Cleocin 2 absolutely why the predisposition to this or that special neurosis exists, but, given the predisposition, it is enough to call out, by some local excitement, any one 626 MODERN VIEWS OF THE NATURE AND of the symptoms which belong to the quasi-physiological group, and the rest will make, their appearance. Just as we can work ourselves up into the outward show of passion for Cleocin Phosphate our own amusement, and without feeling passionate, so the outward shows of passion may be called out, it is fair to think, by some purely reflex cause, without their usual emotional accompaniment, if only there is sufficient co- herence between the different elements of the symptom- complex to form a Cleocin T Acne tolerably definite Cleocin 900 Mg group. In a predisposed person, either a prolonged attack of tachycardia, or an enlargement of the thyroid, or a poison- ing from thyroid secretion, or any one of many causes may bring on the disease. 2. I have tried to point out how this array of symptoms only indicates one of the modes of dissolutions, so to speak, of the nervous system, and that herein the relationship of Graves's disease to the other degenerative neuroses finds itself explained. Even when regarded as a. symptom- complex of agitation and fear, it is still, not only as sub- serving some definite end, that the Cleocin Topical Solution symptom-group is to be looked upon, but in part as a phenomenon of a paralytic or degenerative character. This is indicated by the term embryocardia, which has been used as a substitute for tachycardia, to indicate the degenerative nature of the heart failure. In fine, the best explanation of Graves's disease and of its relation to the affections observed with it, so far as an explanation is possible, seems to me something like the following : The cardinal symptoms of the disease Cleocin Cream Acne are united by a physiological bond, in that they form a group characteristic of strong emotion of Cleocin Iv the nature of expectant fear. Even the conjoined affections are all excitable under the influence of emotion, as an examination of Fere's im- portant volume on the pathology of Antibiotic Cleocin the emotions will show. To a certain extent the numerous symptoms of Graves's